Joyce Huanhuan Chen
APPOINTMENTS
Assistant Professor in Molecular Engineering and in The Ben May Department for Cancer Research. 2020-
Postdoctoral Fellow, Cancer Biology, Weill Cornell Medicine. 2015-2020
EDUCATION
PhD, Biomedical Engineering, Cornell University
MS, Biomedical Engineering, Cornell University
PharmD, Pharmaceutical Sciences, Zhejiang University
AWARDS
2024-2031 NIH Method to Extend Research in Time (MERIT) Award
2023-2026 Department of Defense (DoD) Idea Development Award
2022-2024. Lung Cancer Research Foundation (LCRF) Pilot Project Award
2022-2023. Neuroendocrine Tumor Research Foundation (NETRF) Pilot Project Award
2021-2022. UCCCC-Janet D. Rowley Discovery Fund
2021-2023. Cancer Research Foundation (CRF) Young Investigator
2019. AACR-KCA Young Investigator Award
2019-2024. K99/R00 NIH Pathway to Independence Award
2015-2018. Arnold O. Beckman Foundation Postdoctoral Fellows Award
2018. American Association for Cancer Research (AACR) Scholar-in-Training Award
2013-2014. NIH NCI-Physical Sciences in Oncology (PS-OC) Young Investigator Award
2011-2014. National Science Foundation (NSF) Graduate Research Fellowship
REPRESENTATIVE PUBLICATIONS
Han YL, Yang L, Duan XH, Duan FY, Nilsson-Payant B., …. Chen HJ.* Schwartz R.* Chen SB.* Identification of SARS-CoV-2 Inhibitors using Lung and Colonic Organoids. Nature, 2021. 589. 270-275 (co-corresponding author).
Lian QZ.*Zhang K, Zhang Z, Duan FY, Guo L, Yang L., …Chen ZW., Chen Y., Chen HJ* Differential Effects of Macrophage Subtypes on SARS-CoV-2 Infection in A Human Pluripotent Stem Cell-Derived Model. Nature Communications. 2022. 13: 2028. DOI: 10.1038/s41467-022-29731-5
Chen, HJ.*†, Paron, A.*, Unni, A., Huang, XL., Elemento, O., Snoeck, H., Varmus, H.†, Generation of pulmonary neuroendocrine cells and SCLC-like tumors from human embryonic stem cells Journal of Experimental Medicine, 2019, 216 (3): 674.
Chen, HJ. *, Miller, P. *, Shuler, M.L., a Pumpless Body-on-a-chip Model Using Primary Culture of human Intestinal Cells and 3D Culture of Liver Cells. Lab on a Chip, (2018), 18(14):2036-2046. (article and cover)
Chen, HJ.*, Wei, Z. *, Sun J., Savage, D., Curley, S., Serda, R., Copeland, N.G., Jenkins, N.A. †, Shuler, M.L. †, A recellularized human colon model identifies cancer driver genes. Nature Biotechnology, (2016) 34(8):845-51.
Chen, HJ., Sun, J., Huang, Z., Hou, H., Arcilla, M., Rakhilin, N., Joe, D., Choi, J., Gadamsetty, P., Milsom, J., Nandakumar, G., Longman, R., Zhou, X. K., Edwards, R., Chen J., Chen K. Y., Bu, P., Wang, L., Xu, Y., Munroe, R., Abratte, C., Miller, A. D., Gümüş, Z. H., Shuler, M., Nishimura, N., Edelmann, W., Shen, X., and Lipkin, S., M. Comprehensive models of human primary and metastatic colorectal tumors in immunodeficient and immunocompetent mice by chemokine targeting. Nature Biotechnology, (2015) 33, 656-660.
Chen, HJ., Edwards, R., Tucci, S., Bu, P., Milsom, J., Lee, S., Edelmann, W., Gümüs, ZH., Shen, X., Lipkin, SM., The chemokine receptor 9-chemokine 25 axis suppresses colon cancer invasion and metastasis. Journal of Clinical Investigation. (2012) 122(9):3184–3196.